Progress in the Chemistry of Organic Natural Products 108 [electronic resource] / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, Yoshinori Asakawa, Ji-Kai Liu.Material type: TextSeries: Progress in the Chemistry of Organic Natural Products: 108Publisher: Cham : Springer International Publishing : Imprint: Springer, 2019Edition: 1st ed. 2019Description: V, 296 p. 208 illus., 59 illus. in color. online resourceContent type: text Media type: computer Carrier type: online resourceISBN: 9783030010997Subject(s): Organic chemistry | Pharmaceutical technology | Medicinal chemistry | Organic Chemistry | Pharmaceutical Sciences/Technology | Medicinal ChemistryAdditional physical formats: Printed edition:: No title; Printed edition:: No titleDDC classification: 547 LOC classification: QD415-436Online resources: Texto completo
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Chemistry and biology of selected Mexican medicinal plants -- Biomolecular targets of oxyprenylated phenylpropanoids and polyketides -- Secondary metabolites of endophytic actinomycetes: isolation, synthesis, biosynthesis, and biological activities.
The first contribution summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described. The second contribution provides a detailed survey of the so far reported literature data on the capacities of selected oxyprenylated phenylpropanoids and polyketides to trigger receptors, enzymes, and other types of cellular factors for which they exhibit a high degree of affinity and therefore evoke specifice responses. And the third contribution discusses aspects of endophytic actinobacterial biology and chemistry, including biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives fo the future of microbial biodiscovery, with emphasis on the seondary metabolism of endophytic actinobacteria.